Supplement Excipients Explained: Fillers, Binders, Flow Agents and What "No Fillers, No Binders" Really Means
Turn over almost any supplement bottle and the ingredient list splits in two. Above the line are the vitamins, minerals, botanicals or proteins the customer is paying for. Below it, under "other ingredients", sit the substances nobody asked for: microcrystalline cellulose, magnesium stearate, silicon dioxide, hypromellose, croscarmellose sodium. These are excipients, and they usually account for a large share of what is in the capsule or tablet. This article explains what each class of excipient does, why a manufacturer cannot simply leave them out, which ones regulators have restricted, and what the increasingly common "no fillers, no binders" claim does and does not tell a buyer. Quick answer: Excipients are the non-active ingredients that make a supplement physically possible: fillers give a small dose enough bulk to fill a capsule, binders hold a tablet together, disintegrants make it break apart in the stomach, lubricants and flow agents keep powder movin...